GH220合金渗Al层的逐层相分析

通过物理—化学相分析及其它物理手段对经900℃不同时间时效的GH220合金的渗铝层进行了逐层相分析。用联立方程分别求出离表面不同深度范围内β—NiAl相γ′相的含量。通过修正比重,对取层厚度进行了合理计算。提供了渗铝层中相变趋势。本文把计算过程全部编成程序。对微处理机在相分析中的运用作了初步尝试。     

4G移动通信系统及其关键技术

提出了3G通信系统的局限性,概述了4G通信系统的特点和关键技术,对4G系统网络结构作了简单介绍。     

Regulation of insulin receptor function

Resistance to the biological actions of insulin contributes to the development of type 2 diabetes and risk of cardiovascular disease. A reduced biological response to insulin by tissues results from an impairment in the cascade of phosphorylation events within cells that regulate the activity of enzymes comprising the insulin signaling pathway. In most models of insulin resistance, there is evidence that this decrement in insulin signaling begins with either the activation or substrate kinase activity of the insulin receptor (IR), which is the only component of the pathway that is unique to insulin action. Activation of the IR can be impaired by post-translational modifications of the protein involving serine phosphorylation, or by binding to inhibiting proteins such as PC-1 or members of the SOCS or Grb protein families. The impact of these processes on the conformational changes and phosphorylation events required for full signaling activity, as well as the role of these mechanisms in human disease, is reviewed in this article. Received 3 August 2006; received after revision 1 December 2006; accepted 8 January 2007     

The molecular role of the Rothmund-Thomson-, RAPADILINO- and Baller-Gerold-gene product, RECQL4: recent progress

The RecQ family of DNA helicases is highly conserved throughout evolution and plays an important role in the maintenance of genomic stability in all organisms. Mutations in three of the five known family members in humans, BLM, WRN and RECQL4, give rise to disorders that are characterized by predisposition to cancer and premature aging, emphasizing the importance of studying the RecQ proteins and their cellular activities. Interestingly, three autosomal recessive disorders have been associated with mutations in the RECQL4 gene: Rothmund-Thomson, RAPADILINO, and Baller-Gerold syndromes, thus making RECQL4 unique within the RecQ family of DNA helicases. To date, however, the molecular function of RECQL4 and the possible cellular pathways in which it is involved remain poorly understood. Here, we present an overview of recent findings in connection with RECQL4 and try to highlight different directions the field could head, helping to clarify the role of RECQL4 in preventing tumorigenesis and maintenance of genome integrity in humans. Received 31 October 2006; received after revision 4 January 2007; accepted 5 February 2007     

Eph受体家族和Ephrin-A5在NSCLCs中上调表达及其临床意义

采用荧光实时定量PCR的方法在48个非小细胞肺癌组织以及配对的正常肺组织中检测Eph/ephrin 基因的mRNA水平.发现肺癌组织中EphB4, EphB3 和 ephrin-A5的表达水平与配对的正常肺组织相比分别上调了60%,81%和65%,并具有显著的统计学差异. 而且,统计学分析发现ephrin-A5的表达水平与肿瘤分型、转移、性别、吸烟以及诊断年龄等临床病理学参数之间存在显著的相关性.此外,EphA2的表达水平与肿瘤大小、家族遗传史以及诊断年龄之间也存在显著的相关性.总之,这些结果提示EphB4, EphA2, EphB3 和ephrin-A5 在肺癌的发生和发展过程中可能以一种单独或者协同的形式发挥作用.这些蛋白有可能成为研究和诊断肺癌的重要靶向基因.     

Homology Priority Task Scheduling in μC/OS-Ⅱ Real-Time Kernel

μC/OS-Ⅱ is an open source real-time kernel adopting priority preemptive schedule strategy. Aiming at the problem of μC/OS-Ⅱ failing to support homology priority tasks scheduling, an approach for solution is proposed. The basic idea is adding round-robin scheduling strategy in its original scheduler in order to schedule homology priority tasks through time slice roundrobin. Implementation approach is given in detail. Firstly, the Task Control Block （TCB） is extended. And then, a new priority index table is created, in which each index pointer points to a set of homology priority tasks. Eventually, on the basis of reconstructing μC/OS-Ⅱ real-time kernel, task scheduling module is rewritten. Otherwise, schedulability of homology task supported by modified kernel had been analyzed, and deadline formula of created homology tasks is given. By theoretical analysis and experiment verification, the modified kernel can support homology priority tasks scheduling, meanwhile, it also remains preemptive property of original μC/OS-Ⅱ.     

合成N,N,N'''',N''''-四(2-甲酯基乙基)乙二胺的绿色工艺研究

为了解决合成聚酰胺-胺时回收液处理复杂、能耗大、并污染环境的问题,以合成N,N,N',N'-四(2-甲酯基乙基)乙二胺(TMCEDA)为研究对象,对不同真空度条件下的回收液进行了定性定量分析,在此基础上,采用分段减压蒸馏分离合成TMCEDA中的过量原料与溶剂,直接循环使用真空度在50 kPa-100 kPa的回收液的新工艺.应用气相色谱分析技术跟踪分析循环使用的回收液的成分,结果表明,经过40次循环使用的回收液,仍未见明显的杂质积累现象.该工艺对回收液的直接使用率高达98.0%,实现了TMCEDA的实验室绿色合成,可为其工业化生产提供参考.图7,表2,参11.     

一类次二次Hamilton系统的次调和解的存在性

运用临界点理论中的极小极大方法得到一类次二次Hamilton系统的次调和解的存在性定理.